Epidemiological trends of dengue disease in Thailand (2000-2011): a systematic literature review

PLoS Negl Trop Dis. 2014 Nov 6;8(11):e3241. doi: 10.1371/journal.pntd.0003241. eCollection 2014.

Abstract

A literature survey and analysis was conducted to describe the epidemiology of dengue disease in Thailand reported between 2000 and 2011. The literature search identified 610 relevant sources, 40 of which fulfilled the inclusion criteria defined in the review protocol. Peaks in the number of cases occurred during the review period in 2001, 2002, 2008 and 2010. A shift in age group predominance towards older ages continued through the review period. Disease incidence and deaths remained highest in children aged ≤ 15 years and case fatality rates were highest in young children. Heterogeneous geographical patterns were observed with higher incidence rates reported in the Southern region and serotype distribution varied in time and place. Gaps identified in epidemiological knowledge regarding dengue disease in Thailand provide several avenues for future research, in particular studies of seroprevalence.

Protocol registration: PROSPERO CRD42012002170.

Publication types

  • Research Support, Non-U.S. Gov't
  • Review
  • Systematic Review

MeSH terms

  • Dengue / epidemiology*
  • Dengue Virus / classification*
  • Dengue Virus / immunology
  • Genotype
  • Humans
  • Incidence
  • Seasons
  • Seroepidemiologic Studies
  • Serogroup
  • Thailand / epidemiology

Grants and funding

Sanofi Pasteur sponsored this survey and analysis. The Literature Review Group (including members of Sanofi Pasteur) were responsible for the conception of the literature analysis, development of the protocol, data collection, analysis and interpretation of data, provision of critical comments, writing the paper and approving the final version to be published. All authors were involved in the decision to submit this paper for publication in PLoS NTDs.