Epidemiology of dengue disease in the Philippines (2000-2011): a systematic literature review

PLoS Negl Trop Dis. 2014 Nov 6;8(11):e3027. doi: 10.1371/journal.pntd.0003027. eCollection 2014.

Abstract

This literature analysis describes the available dengue epidemiology data in the Philippines between 2000 and 2011. Of 253 relevant data sources identified, 34, including additional epidemiology data provided by the National Epidemiology Center, Department of Health, Philippines, were reviewed. There were 14 publications in peer reviewed journals, and 17 surveillance reports/sources, which provided variable information from the passive reporting system and show broad trends in dengue incidence, including age group predominance and disease severity. The peer reviewed studies focused on clinical severity of cases, some revealed data on circulating serotypes and genotypes and on the seroepidemiology of dengue including incidence rates for infection and apparent disease. Gaps in the data were identified, and include the absence incidence rates stratified by age, dengue serotype and genotype distribution, disease severity data, sex distribution data, and seroprevalence data.

Publication types

  • Research Support, Non-U.S. Gov't
  • Review
  • Systematic Review

MeSH terms

  • Age Distribution
  • Dengue / epidemiology*
  • Dengue Virus / classification*
  • Dengue Virus / genetics
  • Dengue Virus / immunology
  • Environment
  • Genotype
  • Humans
  • Incidence
  • Philippines / epidemiology
  • Seasons
  • Seroepidemiologic Studies
  • Serogroup
  • Sex Distribution

Grants and funding

Sanofi Pasteur sponsored this survey and analysis. The sponsors of this study formed part of the literature review group. The role of the sponsors in study design, data collection and analysis, decision to publish and preparation of the manuscript is detailed below. The Literature Review Group, which included members of the sponsor Sanofi Pasteur, were responsible for the conception of the literature analysis, development of the protocol, data collection, analysis and interpretation of data, provision of critical comments, writing the paper, and approving the final version to be published. All authors were involved in the decision to submit this paper for publication in PLOS NTD. All authors confirm that they had full access to all data identified during the literature search and analysis.