Direct validation of the restriction of intramolecular rotation hypothesis via the synthesis of novel ortho-methyl substituted tetraphenylethenes and their application in cell imaging

Chem Commun (Camb). 2014 Oct 18;50(81):12058-60. doi: 10.1039/c4cc04241g.

Abstract

We demonstrate a novel synthetic approach to ortho-methyl substituted tetraphenylethene materials, which can be utilised for directly validating the restriction of intramolecular rotation hypothesis as the basic mechanism of aggregation-induced emission phenomenon and cell imaging.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Crystallography, X-Ray
  • Ethylenes / chemical synthesis
  • Ethylenes / chemistry*
  • Ethylenes / metabolism
  • Fluorescent Dyes / chemistry*
  • Fluorescent Dyes / metabolism
  • HeLa Cells
  • Humans
  • Microscopy, Confocal
  • Molecular Conformation

Substances

  • Ethylenes
  • Fluorescent Dyes