Abstract
We report a fatal case of Schizophyllum commune empyema thoracis with cross-reactive cryptococcal antigenemia. In vitro testing confirmed the ability of the fungus to cause a positive cryptococcal antigen latex agglutination system (CALAS) test result. Such a result may lead to delay in diagnosis and treatment, as most strains of S. commune are resistant to fluconazole.
Publication types
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Case Reports
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Research Support, Non-U.S. Gov't
MeSH terms
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Aged
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Antigens, Fungal / blood*
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Cross Reactions*
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Cryptococcus / immunology*
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DNA, Fungal / chemistry
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DNA, Fungal / genetics
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Empyema, Pleural / diagnosis*
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Empyema, Pleural / microbiology
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False Positive Reactions
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Fatal Outcome
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Humans
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Latex Fixation Tests / methods*
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Male
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Molecular Sequence Data
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Mycoses / diagnosis*
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Mycoses / microbiology
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Schizophyllum / isolation & purification*
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Sequence Analysis, DNA
Substances
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Antigens, Fungal
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DNA, Fungal