Impulsivity, cognitive function, and their relationship in heroin-dependent individuals

J Clin Exp Neuropsychol. 2013;35(9):897-905. doi: 10.1080/13803395.2013.828022. Epub 2013 Sep 17.

Abstract

There is mixed evidence concerning cognitive function and heroin dependence. In this study, abstinent heroin-dependent individuals (n = 86) and age- and sex-matched non-drug-using controls (n = 88) were compared on self-report measures of impulsivity and computerized assessments of cognitive function. Abstinent heroin-dependent individuals reported greater motor impulsivity and experience seeking and showed functional weaknesses in cognitive ability, including impulsivity and distractibility (d = 0.28 to 0.49), but not decision making or working memory. Self-reported impulsivity was uncorrelated with cognitive function. These results suggest underlying brain-related factors in heroin dependence and have implications for therapeutic intervention.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adolescent
  • Adult
  • Attention / physiology
  • Cognition / physiology*
  • Drug Users / psychology*
  • Female
  • Heroin Dependence / complications
  • Heroin Dependence / psychology*
  • Humans
  • Impulsive Behavior / complications
  • Impulsive Behavior / psychology*
  • Male
  • Memory, Short-Term / physiology
  • Middle Aged
  • Neuropsychological Tests
  • Self Report