Silver-catalysed intramolecular hydroamination of alkynes with trichloroacetimidates

Chem Commun (Camb). 2013 Oct 18;49(81):9272-4. doi: 10.1039/c3cc45500a.

Abstract

Silver(I) complexes catalyse the intramolecular addition of trichloroacetimidates to alkynes. In the absence of a ligand, the selectivity of the reaction is dependent upon the nature of the counter-anion and solvent. The introduction of non-chelating nitrogeneous ligands suppresses competitive Brønsted acid catalysis, improving the yield and selectivity of the reaction.