The insufficiency intake of dietary micronutrients associated with malnutrition-inflammation score in hemodialysis population

PLoS One. 2013 Jun 25;8(6):e66841. doi: 10.1371/journal.pone.0066841. Print 2013.

Abstract

The relations between dietary micronutrient, nutritional status and inflammation in hemodialysis patients are still unclear. A cross-sectional study was performed in hemodialysis population. 75 hemodialysis patients from South China participated in the dietary and nutritional assessment. Clinical and dietary data were collected. Nutritional status was assessed by Malnutrition-Inflammation Score (MIS) in addition to related anthropometric measurements. And according to the MIS score, the whole hemodialysis patients were divided into normal nutrition group and malnutrition group. The results showed that mid arm circumference (MAC) negatively correlated with MIS (r = -0.425; P = 0.002). The area under the ROC curve (AUC) for MAC was 0.737 (0.614-0.859). Comparing with the normal nutritional group, lower dietary selenium (Se), copper (Cu), iodine (I) and manganese (Mn) intake were observed among patients with malnutrition (P<0.05). While no significant differences of diverse vitamins were found. In conclusion, MAC was effective indicator for assessing nutritional and inflammatory status (P<0.05). The reduction of dietary Se, Cu, I and Mn intake level may be alarming markers for malnutrition and inflammatory status in hemodialysis patients.

Publication types

  • Multicenter Study
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Cross-Sectional Studies
  • Diet*
  • Female
  • Humans
  • Inflammation / diagnosis
  • Inflammation / physiopathology
  • Male
  • Malnutrition / diagnosis
  • Malnutrition / physiopathology*
  • Middle Aged
  • Nutritional Status
  • ROC Curve
  • Renal Dialysis*

Grants and funding

This work was supported in part by National Natural Science Foundation of China (81170647, 91029742 and 30973207) and the Fok Ying-Tong Education Foundation for Young Teachers in the Higher Education Institutions of China (132030) to Hui Huang. The funders had no role in study design, data collection and analysis, decision to publish, or preparation of the manuscript.