Convergent synthesis of MUC1 glycopeptides via serine ligation

Chem Commun (Camb). 2013 Jul 14;49(55):6200-2. doi: 10.1039/c3cc42573h.

Abstract

Syntheses of MUC1 glycopeptides (40-mer and 80-mer) are described. The convergent synthesis was achieved by native serine ligation using side-chain unprotected glycopeptide segments.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Aldehydes / chemistry
  • Chromatography, High Pressure Liquid
  • Glycopeptides / chemistry*
  • Mucin-1 / chemistry*
  • Serine / chemistry*

Substances

  • Aldehydes
  • Glycopeptides
  • Mucin-1
  • salicylaldehyde
  • Serine