Abstract
A silver complex of N,N'-disubstituted cyclic thiourea inhibits inflammatory cytokine-stimulated NF-κB activity via IκB kinase inactivation.
Publication types
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Research Support, Non-U.S. Gov't
MeSH terms
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Anti-Inflammatory Agents / chemistry
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Anti-Inflammatory Agents / pharmacology*
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HeLa Cells
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Humans
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I-kappa B Kinase / antagonists & inhibitors*
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NF-kappa B / antagonists & inhibitors
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NF-kappa B / genetics
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Protein Kinase Inhibitors / chemistry
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Silver / chemistry
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Silver / pharmacology*
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Thiourea / chemistry
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Thiourea / pharmacology*
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Tumor Necrosis Factor-alpha / pharmacology
Substances
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Anti-Inflammatory Agents
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NF-kappa B
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Protein Kinase Inhibitors
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Tumor Necrosis Factor-alpha
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Silver
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I-kappa B Kinase
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Thiourea