Haemophagocytic lymphohistiocytosis: an uncommon clinical presentation of tuberculosis

Hong Kong Med J. 2012 Dec;18(6):517-25.

Abstract

Secondary haemophagocytic lymphohistiocytosis is a rare but fatal complication of tuberculosis. We describe two cases, and review the local and international experience on the management of this clinical entity. Prompt treatment with anti-tuberculous drugs forms the cornerstone of therapeutic success.

Publication types

  • Case Reports
  • Review

MeSH terms

  • Aged
  • Aged, 80 and over
  • Antitubercular Agents / therapeutic use
  • Female
  • Humans
  • Lymphohistiocytosis, Hemophagocytic / diagnosis
  • Lymphohistiocytosis, Hemophagocytic / drug therapy
  • Lymphohistiocytosis, Hemophagocytic / etiology*
  • Male
  • Mycobacterium tuberculosis / isolation & purification*
  • Tuberculosis / complications*
  • Tuberculosis / diagnosis
  • Tuberculosis / drug therapy

Substances

  • Antitubercular Agents