Possible efficacy of Lavender and Tea tree oils in the treatment of young women affected by mild idiopathic hirsutism

J Endocrinol Invest. 2013 Jan;36(1):50-4. doi: 10.3275/8766. Epub 2012 Nov 26.

Abstract

Background: Hirsutism is defined as the presence of excessive terminal hair in androgen-dependent areas of a woman's body. Regarding this it has been suggested that Lavender and Tea tree oils may have antiandrogenic activities.

Aim: To evaluate therapy based on Lavender and Tea tree oils in women suffering from mild idiopathic hirsutism (IH).

Subjects and methods: A prospective, open-label, placebo- controlled, randomized study was performed: women affected by mild IH were randomly assigned to receive oil spray containing Lavender and Tea tree oils (group T) (no. = 12) or placebo (group P) (no. = 12) twice a day for 3 months in areas affected by hirsutism. Evaluation of hirsutism was carried out at baseline and after 3 months by Ferriman-Gallwey score and by measuring hair diameter taken from some body areas. A hematological and hormonal evaluation was carried out at baseline and after 3 months.

Results: No significant variations were found in any of the hormones studied in groups T and P between baseline and after 3 months. A statistically significant decrease of hirsutism total score and of hair diameter was found in group T, while no statistically significant difference in these two parameters was observed in group P; in group T percentual reduction of hair diameter was significantly greater than in group P.

Conclusions: Lavender and Tea tree oils applied locally on skin could be effective in reducing mild IH; this treatment could represent a safe, economic and practical instrument in the cure of this disease.

Publication types

  • Randomized Controlled Trial
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adult
  • Androgen Antagonists / therapeutic use*
  • Anti-Infective Agents, Local / therapeutic use*
  • Female
  • Hirsutism / drug therapy*
  • Humans
  • Lavandula / chemistry*
  • Phytotherapy*
  • Prospective Studies
  • Tea Tree Oil / therapeutic use*
  • Treatment Outcome

Substances

  • Androgen Antagonists
  • Anti-Infective Agents, Local
  • Tea Tree Oil