Reemergence of Chikungunya virus in Cambodia

Emerg Infect Dis. 2012 Dec;18(12):2066-9. doi: 10.3201/eid1812.120471.

Abstract

Chikungunya virus (CHIKV), probably Asian genotype, was first detected in Cambodia in 1961. Despite no evidence of acute or recent CHIKV infections since 2000, real-time reverse transcription PCR of serum collected in 2011 detected CHIKV, East Central South African genotype. Spatiotemporal patterns and phylogenetic clustering indicate that the virus probably originated in Thailand.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adolescent
  • Adult
  • Alphavirus Infections / epidemiology*
  • Antibodies, Viral / blood
  • Antibodies, Viral / immunology
  • Cambodia / epidemiology
  • Chikungunya virus / classification
  • Chikungunya virus / genetics*
  • Chikungunya virus / immunology
  • Child
  • Child, Preschool
  • Communicable Diseases, Emerging / epidemiology*
  • Disease Outbreaks*
  • Female
  • Humans
  • Immunoglobulin M / blood
  • Immunoglobulin M / immunology
  • Male
  • Middle Aged
  • Phylogeny
  • Public Health Surveillance
  • RNA, Viral
  • Viral Proteins / genetics
  • Young Adult

Substances

  • Antibodies, Viral
  • Immunoglobulin M
  • RNA, Viral
  • Viral Proteins