Clinical utility gene card for: Lynch syndrome (MLH1, MSH2, MSH6, PMS2, EPCAM) - update 2012

Eur J Hum Genet. 2013 Jan;21(1). doi: 10.1038/ejhg.2012.164. Epub 2012 Aug 15.
No abstract available

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adaptor Proteins, Signal Transducing / genetics*
  • Adenosine Triphosphatases / genetics*
  • Antigens, Neoplasm / genetics*
  • Cell Adhesion Molecules / genetics*
  • Colorectal Neoplasms, Hereditary Nonpolyposis / diagnosis*
  • Colorectal Neoplasms, Hereditary Nonpolyposis / epidemiology
  • Colorectal Neoplasms, Hereditary Nonpolyposis / genetics*
  • DNA Repair Enzymes / genetics*
  • DNA-Binding Proteins / genetics*
  • Epithelial Cell Adhesion Molecule
  • Female
  • Genetic Testing / methods
  • Humans
  • Life Style
  • Mismatch Repair Endonuclease PMS2
  • MutL Protein Homolog 1
  • MutS Homolog 2 Protein / genetics*
  • Mutation
  • Nuclear Proteins / genetics*
  • Predictive Value of Tests
  • Pregnancy
  • Prenatal Diagnosis
  • Sensitivity and Specificity

Substances

  • Adaptor Proteins, Signal Transducing
  • Antigens, Neoplasm
  • Cell Adhesion Molecules
  • DNA-Binding Proteins
  • EPCAM protein, human
  • Epithelial Cell Adhesion Molecule
  • G-T mismatch-binding protein
  • MLH1 protein, human
  • Nuclear Proteins
  • Adenosine Triphosphatases
  • PMS2 protein, human
  • MSH2 protein, human
  • Mismatch Repair Endonuclease PMS2
  • MutL Protein Homolog 1
  • MutS Homolog 2 Protein
  • DNA Repair Enzymes