How to build a DNA unwinding machine

Structure. 2012 Jul 3;20(7):1127-8. doi: 10.1016/j.str.2012.06.006.

Abstract

In this issue of Structure, He and colleagues present the crystal structure of the phage T4 Dda helicase bound to DNA, providing new insights into how this protein efficiently couples single-stranded DNA translocation to DNA strand separation.

Publication types

  • Comment

MeSH terms

  • Bacteriophage T4 / metabolism*
  • DNA / chemistry*
  • DNA Helicases / chemistry*
  • DNA, Single-Stranded / chemistry*
  • Viral Proteins / chemistry*

Substances

  • DNA, Single-Stranded
  • Viral Proteins
  • DNA
  • DNA Helicases
  • dda DNA helicase protein, Bacteriophage T4