Surveillance of transmitted HIV drug resistance using matched plasma and dried blood spot specimens from voluntary counseling and testing sites in Ho Chi Minh City, Vietnam, 2007-2008

Clin Infect Dis. 2012 May;54 Suppl 4(Suppl 4):S343-7. doi: 10.1093/cid/cir1049.

Abstract

During 2007-2008, surveillance of transmitted human immunodeficiency virus (HIV) drug resistance (TDR) was performed following World Health Organization guidance among clients with newly diagnosed HIV infection attending voluntary counseling and testing (VCT) sites in Ho Chi Minh City (HCMC), Vietnam. Moderate (5%-15%) TDR to nonnucleoside reverse-transcriptase inhibitors (NNRTIs) was observed among VCT clients aged 18-21 years. Follow-up surveillance of TDR in HCMC and other geographic regions of Vietnam is warranted. Data generated will guide the national HIV drug resistance surveillance strategy and support selection of current and future first-line antiretroviral therapy and HIV prevention programs.

Publication types

  • Research Support, N.I.H., Extramural
  • Research Support, U.S. Gov't, P.H.S.

MeSH terms

  • Ambulatory Care Facilities
  • Anti-Retroviral Agents / pharmacology*
  • Blood Chemical Analysis / methods*
  • Dried Blood Spot Testing
  • Drug Resistance, Viral
  • Genotyping Techniques
  • HIV / classification*
  • HIV / drug effects
  • HIV / genetics
  • HIV Infections / blood*
  • HIV Infections / epidemiology*
  • HIV Infections / transmission
  • HIV Infections / virology
  • Humans
  • Population Surveillance
  • Vietnam / epidemiology
  • Voluntary Programs
  • Young Adult

Substances

  • Anti-Retroviral Agents