A selective reaction-based fluorescent probe for detecting cobalt in living cells

Chem Commun (Camb). 2012 May 28;48(43):5268-70. doi: 10.1039/c2cc31681a. Epub 2012 Apr 24.

Abstract

A reaction-based strategy exploiting cobalt-mediated oxidative C-O bond cleavage affords a selective turn-on fluorescent probe for paramagnetic Co(2+) in water and in living cells.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Carbon / chemistry
  • Cell Line, Tumor
  • Cobalt / chemistry*
  • Fluoresceins / chemical synthesis
  • Fluoresceins / chemistry*
  • Fluorescent Dyes / chemistry*
  • Humans
  • Magnetics
  • Microscopy, Fluorescence
  • Oxidation-Reduction
  • Oxygen / chemistry
  • Water / chemistry

Substances

  • Fluoresceins
  • Fluorescent Dyes
  • Water
  • Cobalt
  • Carbon
  • Oxygen