Functional specificity in the modulation of novelty exposure effects by reliability of maternal care

Behav Brain Res. 2012 Jan 1;226(1):345-50. doi: 10.1016/j.bbr.2011.08.047. Epub 2011 Sep 6.

Abstract

Using the within-litter neonatal novelty exposure procedure, we manipulated newborn pups' environmental novelty independently from natural variations in maternal care. To better translate animal models to human development studies, we introduce a measure for maternal care reliability. We examined how this reliability modulates novelty-exposure-induced effects on offspring cognitive, social, and emotional development and show that maternal care reliability acts in a function-specific manner. We discuss our results within the framework of a maternal reliability-based modulation model.

MeSH terms

  • Animals
  • Animals, Newborn
  • Behavior, Animal / physiology*
  • Emotions / physiology*
  • Environment*
  • Exploratory Behavior / physiology*
  • Female
  • Handling, Psychological
  • Maternal Behavior / physiology*
  • Rats
  • Rats, Long-Evans
  • Social Behavior
  • Stress, Psychological / physiopathology