Socio-demographic and clinical profiles of paranoid and nonparanoid schizophrenia: a prospective, multicenter study in China

Perspect Psychiatr Care. 2011 Jul;47(3):126-30. doi: 10.1111/j.1744-6163.2010.00281.x. Epub 2010 Nov 3.

Abstract

Purpose: This study aimed to explore the socio-demographic and clinical characteristics of paranoid and nonparanoid subtypes of schizophrenia.

Design and methods: In a multicenter, randomized, controlled, longitudinal study, 374 clinically stable schizophrenia patients were interviewed at entry with standardized assessment instruments and followed for 12-26 months.

Findings: In the multivariate analysis, male sex, married marital status, urban abode, and more frequent relapse over the study period were independently associated with paranoid schizophrenia.

Practice implications: The socio-demographic and clinical characteristics of Chinese patients with the paranoid subtype of schizophrenia are different from those of their Caucasian counterparts who are more likely to be women and have a better outcome.

Publication types

  • Multicenter Study
  • Randomized Controlled Trial
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adult
  • Age Factors
  • Age of Onset
  • Antipsychotic Agents / therapeutic use
  • China
  • Female
  • Humans
  • Logistic Models
  • Male
  • Marital Status
  • Prospective Studies
  • Psychiatric Status Rating Scales
  • Schizophrenia / drug therapy
  • Schizophrenia, Paranoid / drug therapy
  • Schizophrenia, Paranoid / psychology*
  • Schizophrenic Psychology*
  • Sex Factors
  • Socioeconomic Factors
  • Statistics, Nonparametric
  • Treatment Outcome

Substances

  • Antipsychotic Agents