A case of a dento-alveolar abscess due to a polymicrobial infection with a yeast, Candida guilliermondii and two other oral bacteria are described. A review of the literature has revealed only a single case of an odontogenic abscess due to Candida species and we believe this to be the first report of a dentoalveolar infection where Candida guilliermondii is associated as a co-pathogen.