HKGreen-3: a rhodol-based fluorescent probe for peroxynitrite

Org Lett. 2010 Nov 5;12(21):4932-5. doi: 10.1021/ol102182j.

Abstract

A novel fluorescent probe, HKGreen-3, for sensing peroxynitrite is designed on the basis of the rhodol scaffold and a peroxynitrite-specific oxidation reaction. The probe turns out to be highly sensitive and selective for detecting peroxynitrite in both chemical and biological systems.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Animals
  • Cell Line
  • Fluoresceins / analysis
  • Fluoresceins / chemistry*
  • Fluorescent Dyes / analysis
  • Fluorescent Dyes / chemistry*
  • Mice
  • Molecular Structure
  • Peroxynitrous Acid / analysis
  • Peroxynitrous Acid / chemistry*

Substances

  • Fluoresceins
  • Fluorescent Dyes
  • Peroxynitrous Acid