Cholera toxin production by the El Tor variant of Vibrio cholerae O1 compared to prototype El Tor and classical biotypes

J Ghosh-Banerjee; M Senoh; T Takahashi; T Hamabata; S Barman; H Koley; A K Mukhopadhyay; T Ramamurthy; S Chatterjee; M Asakura; S Yamasaki; G B Nair; Y Takeda

doi:10.1128/JCM.00799-10

Cholera toxin production by the El Tor variant of Vibrio cholerae O1 compared to prototype El Tor and classical biotypes

J Clin Microbiol. 2010 Nov;48(11):4283-6. doi: 10.1128/JCM.00799-10. Epub 2010 Sep 1.

Authors

J Ghosh-Banerjee¹, M Senoh, T Takahashi, T Hamabata, S Barman, H Koley, A K Mukhopadhyay, T Ramamurthy, S Chatterjee, M Asakura, S Yamasaki, G B Nair, Y Takeda

Affiliation

¹ National Institute of Cholera and Enteric Diseases, Kolkata, India.

Abstract

Vibrio cholerae O1 El Tor variant strains produced much more cholera toxin than did prototype El Tor strains. The amount of cholera toxin produced by El Tor variant strains both in vitro and in vivo was more or less equivalent to that produced by classical strains.

Publication types

Comparative Study
Research Support, Non-U.S. Gov't

MeSH terms

Animals
Blotting, Western
Cholera Toxin / biosynthesis*
Cholera Toxin / toxicity
Culture Media / chemistry
Humans
Ileum / pathology
Rabbits
Vibrio cholerae O1 / classification*
Vibrio cholerae O1 / pathogenicity*
Virulence Factors / biosynthesis*
Virulence Factors / toxicity

Substances

Culture Media
Virulence Factors
Cholera Toxin