Palladium-catalyzed oxime assisted intramolecular dioxygenation of alkenes with 1 atm of air as the sole oxidant

Ming-Kui Zhu; Jun-Feng Zhao; Teck-Peng Loh

doi:10.1021/ja100716x

Palladium-catalyzed oxime assisted intramolecular dioxygenation of alkenes with 1 atm of air as the sole oxidant

J Am Chem Soc. 2010 May 12;132(18):6284-5. doi: 10.1021/ja100716x.

Authors

Ming-Kui Zhu¹, Jun-Feng Zhao, Teck-Peng Loh

Affiliation

¹ Division of Chemistry and Biological Chemistry, School of Physical and Mathematical Sciences, Nanyang Technological University, Singapore 637371.

PMID: 20394368
DOI: 10.1021/ja100716x

Abstract

This paper describes a palladium-catalyzed oxime assisted intramolecular dioxygenation of alkenes by using 1 atm of air as the sole oxidant under extremely mild conditions, which demonstrated the feasibility of incorporating atmospheric oxygen into synthetically useful products under 1 atm of air at room temperature.