Comparative host gene transcription by microarray analysis early after infection of the Huh7 cell line by SARS coronavirus and human coronavirus 229E

Hong Kong Med J. 2009 Dec:15 Suppl 9:23-6.

Abstract

During the early stages of infection, SARS-CoV produces more severe perturbation of host cell gene expression in a human epithelial cell line of liver origin than the HCoV-229E.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Cell Line, Tumor
  • Coronavirus 229E, Human / metabolism
  • Coronavirus Infections / metabolism*
  • Gene Expression Regulation
  • Humans
  • Microarray Analysis / methods
  • Severe Acute Respiratory Syndrome / metabolism*
  • Severe acute respiratory syndrome-related coronavirus / metabolism
  • Transcription, Genetic*