Encephalopathy and neuropathy following ingestion of a Chinese herbal broth containing podophyllin

J Neurol Sci. 1991 Jan;101(1):107-13. doi: 10.1016/0022-510x(91)90024-2.

Abstract

Two patients developed podophyllin intoxication following ingestion of a broth of the Chinese herb guijiu. The neurological manifestations are described and the pathology of the peripheral neuropathy is fully documented with ultrastructural and quantitative studies.

Publication types

  • Case Reports

MeSH terms

  • Adult
  • Brain / drug effects
  • Brain / pathology
  • Brain / physiopathology*
  • Brain Diseases / chemically induced*
  • Brain Diseases / pathology
  • Brain Diseases / physiopathology
  • Follow-Up Studies
  • Hong Kong
  • Humans
  • Male
  • Medicine, Chinese Traditional*
  • Motor Neurons / physiology
  • Nervous System Diseases / chemically induced
  • Nervous System Diseases / pathology
  • Nervous System Diseases / physiopathology*
  • Neural Conduction
  • Neurons, Afferent / physiology
  • Neurotoxins*
  • Optic Nerve / drug effects
  • Optic Nerve / pathology
  • Optic Nerve / physiopathology*
  • Peripheral Nerves / drug effects
  • Peripheral Nerves / physiopathology
  • Phytotherapy*
  • Podophyllin / poisoning*

Substances

  • Neurotoxins
  • Podophyllin