Abstract
We report three cases of ileocolic mucormycosis in adult immunocompromised patients presenting as acute abdomen. All patients underwent laparotomy but two of them died from multiorgan failure before the diagnoses were confirmed. The diagnosis of gastrointestinal mucormycosis is rarely suspected, and antemortem diagnosis is made in only 25%-50% of cases. These cases illustrate the difficulty encountered by surgeons in managing acute abdomen in neutropenic patients with hematological malignancy. The management of colonic mucormycosis in the published literature is also reviewed.
MeSH terms
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Abdomen, Acute / immunology
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Abdomen, Acute / microbiology
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Adult
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Aged
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Antifungal Agents / therapeutic use
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Antineoplastic Agents / adverse effects*
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Colonic Diseases / diagnosis*
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Colonic Diseases / immunology
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Colonic Diseases / microbiology
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Colonic Diseases / therapy
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Fatal Outcome
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Female
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Hematologic Neoplasms / complications
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Hematologic Neoplasms / immunology
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Hematologic Neoplasms / therapy*
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Humans
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Ileal Diseases / diagnosis*
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Ileal Diseases / immunology
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Ileal Diseases / microbiology
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Ileal Diseases / therapy
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Immunocompromised Host*
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Laparotomy
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Male
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Middle Aged
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Mucormycosis / diagnosis*
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Mucormycosis / immunology
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Mucormycosis / microbiology
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Mucormycosis / therapy
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Multiple Organ Failure / immunology
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Multiple Organ Failure / microbiology
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Neutropenia / immunology
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Radiotherapy, Adjuvant / adverse effects
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Treatment Outcome
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Young Adult
Substances
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Antifungal Agents
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Antineoplastic Agents