Medical management update: Peutz Jeghers syndrome

Paola Higham; Faizan Alawi; Eric T Stoopler

doi:10.1016/j.tripleo.2009.08.022

Medical management update: Peutz Jeghers syndrome

Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 2010 Jan;109(1):5-11. doi: 10.1016/j.tripleo.2009.08.022.

Authors

Paola Higham¹, Faizan Alawi, Eric T Stoopler

Affiliation

¹ Department of Oral Medicine, University of Pennsylvania School of Dental Medicine, Philadelphia, PA, USA.

PMID: 20123375
DOI: 10.1016/j.tripleo.2009.08.022

Abstract

Peutz Jeghers syndrome (PJS) is an autosomal dominant disease characterized by hamartomatous polyposis and distinct mucocutaneous pigmentation. PJS is associated with an increased risk for several cancers and other complications such as small intestine intussusception, short bowel syndrome, and anemia. Medical management mainly consists of treatment of the polyps and surveillance. This medical management update will review clinical concepts, therapeutic advances, and emphasize features of PJS important to the oral health care provider.

Publication types

Review

MeSH terms

Dental Care for Chronically Ill*
Diagnosis, Differential
Humans
Melanosis / etiology*
Mouth Diseases / etiology*
Peutz-Jeghers Syndrome* / complications
Peutz-Jeghers Syndrome* / diagnosis
Peutz-Jeghers Syndrome* / therapy