Abstract
A 15-year-old girl being treated with imatinib for chronic myelogenous leukemia (CML) presented with acute vision loss in her right eye accompanied by swelling of the right side of her neck. On examination, she was found to have disk and macular edema of the right eye. Fine-needle aspiration and excisional biopsies of an enlarged submandibular lymph node were negative for malignancy. Although initial serologies were equivocal for Bartonella henselae, repeat serologies performed 1 week later upon the appearance of a macular star were positive. This is the first reported case of B. henselae in a patient with CML.
MeSH terms
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Adolescent
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Anti-Bacterial Agents / therapeutic use
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Antibodies, Bacterial / blood
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Antineoplastic Agents / therapeutic use
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Bartonella henselae / immunology
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Bartonella henselae / isolation & purification*
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Benzamides
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Cat-Scratch Disease / diagnosis
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Cat-Scratch Disease / drug therapy
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Cat-Scratch Disease / microbiology*
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Doxycycline / therapeutic use
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Eye Infections, Bacterial* / diagnosis
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Eye Infections, Bacterial* / drug therapy
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Eye Infections, Bacterial* / microbiology
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Female
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Fluorescein Angiography
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Humans
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Imatinib Mesylate
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Immunoglobulin G / blood
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Leukemia, Myelogenous, Chronic, BCR-ABL Positive / complications*
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Leukemia, Myelogenous, Chronic, BCR-ABL Positive / drug therapy
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Macular Edema / microbiology
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Magnetic Resonance Imaging
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Papilledema / microbiology
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Piperazines / therapeutic use
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Pyrimidines / therapeutic use
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Retinitis / diagnosis
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Retinitis / drug therapy
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Retinitis / microbiology*
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Tomography, Optical Coherence
Substances
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Anti-Bacterial Agents
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Antibodies, Bacterial
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Antineoplastic Agents
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Benzamides
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Immunoglobulin G
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Piperazines
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Pyrimidines
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Imatinib Mesylate
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Doxycycline