Clinical and molecular epidemiology of human parainfluenza virus 4 infections in hong kong: subtype 4B as common as subtype 4A

J Clin Microbiol. 2009 May;47(5):1549-52. doi: 10.1128/JCM.00047-09. Epub 2009 Mar 4.

Abstract

In this 1-year study, 35 (1.2%) of 2,912 nasopharyngeal aspirates were positive for human parainfluenza virus 4 (HPIV4) by reverse transcription-PCR. Patients with HPIV4 infection were mainly young children and immunocompromised adults. In contrast to the reported predominance of HPIV4A infection, molecular subtyping revealed that 15 (44%) cases were caused by HPIV4B.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adolescent
  • Adult
  • Aged
  • Aged, 80 and over
  • Child
  • Child, Preschool
  • Cluster Analysis
  • Female
  • Genotype
  • Hong Kong / epidemiology
  • Humans
  • Infant
  • Male
  • Middle Aged
  • Molecular Epidemiology
  • Molecular Sequence Data
  • Nasopharynx / virology
  • Parainfluenza Virus 4, Human / classification*
  • Parainfluenza Virus 4, Human / genetics
  • Parainfluenza Virus 4, Human / isolation & purification*
  • RNA, Viral / genetics
  • Reverse Transcriptase Polymerase Chain Reaction
  • Rubulavirus Infections / epidemiology*
  • Rubulavirus Infections / virology
  • Sequence Analysis, DNA
  • Young Adult

Substances

  • RNA, Viral

Associated data

  • GENBANK/FJ608669
  • GENBANK/FJ608670
  • GENBANK/FJ608671
  • GENBANK/FJ608672
  • GENBANK/FJ608673
  • GENBANK/FJ608674
  • GENBANK/FJ608675
  • GENBANK/FJ608676
  • GENBANK/FJ608677
  • GENBANK/FJ608678
  • GENBANK/FJ608679
  • GENBANK/FJ608680
  • GENBANK/FJ608681
  • GENBANK/FJ608682
  • GENBANK/FJ608683
  • GENBANK/FJ608684
  • GENBANK/FJ608685
  • GENBANK/FJ608686
  • GENBANK/FJ608687
  • GENBANK/FJ608688
  • GENBANK/FJ608689
  • GENBANK/FJ608690
  • GENBANK/FJ608691
  • GENBANK/FJ608692
  • GENBANK/FJ608693
  • GENBANK/FJ608694
  • GENBANK/FJ608695
  • GENBANK/FJ608696
  • GENBANK/FJ608697
  • GENBANK/FJ608698
  • GENBANK/FJ608699
  • GENBANK/FJ608700
  • GENBANK/FJ608701
  • GENBANK/FJ608702