Human serum albumen enhanced resonance light scattering of dyes

Jia Runping; Zhai Honglin; Shen Yan; Chen Xingguo; Hu Zhide

doi:10.1016/j.talanta.2004.02.030

Human serum albumen enhanced resonance light scattering of dyes

Talanta. 2004 Oct 8;64(2):355-60. doi: 10.1016/j.talanta.2004.02.030.

Authors

Jia Runping¹, Zhai Honglin, Shen Yan, Chen Xingguo, Hu Zhide

Affiliation

¹ College of Chemistry & Chemical Engineering, Lanzhou University, Lanzhou 730000, PR China.

PMID: 18969611
DOI: 10.1016/j.talanta.2004.02.030

Abstract

For the first time, the relationship between the structural parameters of dye molecule and the enhanced resonance light scattering (RLS) of dye-human serum albumen (HSA) was investigated using chemometrics technique. The data set of the enhanced RLS intensity of the dye-HSA was obtained under the same experimental conditions for 22 dyes. After calculated with HyperChem software and selected by stepwise regression approach, six structural parameters for the maximum RLS wavelength were used in multivariable linear regression (MLR) (R=0.932), seven structural parameters for the corresponding enhanced RLS intensity were employed by MLR (R=0.934). According to these models, the maximum RLS wavelength and the enhanced RLS intensity are both attributed to the spatial structure and energies of dye.