Abstract
An arene-terminated epoxy olefin cyclization was promoted by a water-tolerant Lewis acid to give tri- and tetracyclic 3beta-hydroxy terpenoids and steroid derivatives in 57 and 37% yields, respectively, per new formed ring up to 75%.
Publication types
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Research Support, Non-U.S. Gov't
MeSH terms
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Alkenes / chemistry*
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Crystallography, X-Ray
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Cyclization
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Epoxy Compounds / chemical synthesis*
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Indicators and Reagents
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Indium / chemistry*
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Models, Molecular
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Molecular Conformation
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Solvents
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Steroids / chemical synthesis
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Terpenes / chemical synthesis
Substances
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Alkenes
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Epoxy Compounds
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Indicators and Reagents
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Solvents
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Steroids
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Terpenes
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Indium