Non-surgical periodontal therapy with adjunctive chlorhexidine use in adults with down syndrome: a prospective case series

J Periodontol. 2008 Feb;79(2):379-85. doi: 10.1902/jop.2008.070247.

Abstract

Background: Subjects with Down syndrome (DS) experience a high prevalence of periodontal disease, and the management of this disease in subjects with DS is a challenge for oral health care providers. The purpose of this case series was to follow the periodontal healing response changes over a 12-month period after non-surgical mechanical periodontal therapy with the adjunctive use of chlorhexidine and monthly recalls in adults with DS who presented initially with chronic periodontitis.

Methods: Twenty-one subjects with DS (14 males and seven females; 25.3 +/- 5.5 years of age) with reported mild-to-moderate learning disabilities and chronic periodontitis were recruited and treated by non-surgical mechanical periodontal therapy (followed by monthly recalls) and the adjunctive use of chlorhexidine gel for toothbrushing and chlorhexidine mouthwash twice daily. Clinical data were recorded.

Results: After 12 months of non-surgical mechanical periodontal therapy, the mean percentage of sites with plaque decreased from 84.1% to 23.6%, and the mean number of sites with bleeding on probing decreased from 82.1% to 29.5%. Mean probing depth decreased from 3.2 to 1.8 mm, with a mean clinical attachment level gain of 0.6 mm.

Conclusions: Satisfactory healing responses were achieved following non-surgical mechanical periodontal therapy with the adjunctive use of chlorhexidine and monthly recalls in adults with DS with chronic periodontitis and mild-to-moderate learning disabilities. Such a treatment regimen seems appropriate and beneficial for adults with DS and chronic periodontitis.

MeSH terms

  • Adult
  • Anti-Infective Agents, Local / administration & dosage*
  • Chlorhexidine / administration & dosage*
  • Dental Care for Chronically Ill*
  • Dental Plaque / complications
  • Dental Plaque / therapy
  • Dental Scaling
  • Down Syndrome / complications*
  • Female
  • Gels
  • Humans
  • Male
  • Mouthwashes / therapeutic use
  • Periodontitis / complications*
  • Periodontitis / drug therapy
  • Periodontitis / therapy*
  • Prospective Studies
  • Toothpastes / therapeutic use

Substances

  • Anti-Infective Agents, Local
  • Gels
  • Mouthwashes
  • Toothpastes
  • Chlorhexidine