WNT5A is epigenetically silenced in hematologic malignancies and inhibits leukemia cell growth as a tumor suppressor

Blood. 2007 Dec 1;110(12):4130-2. doi: 10.1182/blood-2007-06-094870.
No abstract available

Publication types

  • Letter

MeSH terms

  • Cell Line, Tumor
  • Epigenesis, Genetic*
  • Gene Expression Regulation, Leukemic*
  • Gene Silencing*
  • Hematologic Neoplasms / genetics
  • Hematologic Neoplasms / metabolism*
  • Hematologic Neoplasms / pathology
  • Humans
  • Leukemia / genetics
  • Leukemia / metabolism*
  • Leukemia / pathology
  • Proto-Oncogene Proteins / biosynthesis*
  • Proto-Oncogene Proteins / genetics
  • Tumor Suppressor Proteins / biosynthesis*
  • Tumor Suppressor Proteins / genetics
  • Wnt Proteins / biosynthesis*
  • Wnt Proteins / genetics
  • Wnt-5a Protein

Substances

  • Proto-Oncogene Proteins
  • Tumor Suppressor Proteins
  • WNT5A protein, human
  • Wnt Proteins
  • Wnt-5a Protein