Some uses of transition metal complexes as anti-cancer and anti-HIV agents

Dalton Trans. 2007 Nov 21:(43):4884-92. doi: 10.1039/b705079h. Epub 2007 Sep 18.

Abstract

The success of the clinical uses of cisplatin, cis-[Pt(II)(NH(3))(2)Cl(2)], has stimulated considerable interest in using other metal complexes as new therapeutic agents. This perspective describes our recent work on several classes of gold(III), platinum(II), ruthenium(II, III, IV), iron(II) and vanadium(IV) complexes for anti-cancer and anti-HIV treatments.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Anti-HIV Agents / chemistry
  • Anti-HIV Agents / pharmacology*
  • Antineoplastic Agents / chemistry
  • Antineoplastic Agents / pharmacology*
  • Crystallography, X-Ray
  • Drug Screening Assays, Antitumor
  • Metals / chemistry
  • Metals / pharmacology*
  • Models, Molecular
  • Transition Elements / chemistry
  • Transition Elements / pharmacology*

Substances

  • Anti-HIV Agents
  • Antineoplastic Agents
  • Metals
  • Transition Elements