Antibiotic-loaded cement articulating spacer for 2-stage reimplantation in infected total knee arthroplasty: a simple and economic method

J Arthroplasty. 2007 Oct;22(7):1060-6. doi: 10.1016/j.arth.2007.04.028.

Abstract

We presented a simple and economic method of preparing articulating antibiotic-loaded cement spacers for treatment of infection after total knee arthroplasty. From 1996 to 2004, 28 infected total knee arthroplasties were treated with 2-stage reimplantation. Static spacers were used in 7 knees, and articulating spacers were used in 21 knees. A minimum of 2 years' follow-up after final treatment was evaluated. In the static group, 1 (14%) knee had recurrence of infection. In the articulating group, 2 (9%) knees had recurrence of infection with the original organism. Patients receiving articulating spacer had better range of motion, better knee score, and less bone loss than patients with static spacer.

MeSH terms

  • Anti-Bacterial Agents / adverse effects
  • Anti-Bacterial Agents / economics
  • Anti-Bacterial Agents / therapeutic use*
  • Arthritis, Rheumatoid / surgery
  • Arthroplasty, Replacement, Knee / adverse effects*
  • Arthroplasty, Replacement, Knee / economics
  • Arthroplasty, Replacement, Knee / methods
  • Bacterial Infections / drug therapy
  • Bacterial Infections / economics
  • Bacterial Infections / etiology*
  • Bone Cements / adverse effects
  • Bone Cements / economics
  • Bone Cements / therapeutic use*
  • Follow-Up Studies
  • Humans
  • Joint Diseases / economics
  • Joint Diseases / microbiology
  • Joint Diseases / surgery
  • Knee Joint / microbiology*
  • Knee Joint / physiology
  • Knee Joint / surgery
  • Osteoarthritis, Knee / surgery
  • Prosthesis-Related Infections / drug therapy*
  • Range of Motion, Articular / physiology
  • Recurrence
  • Reoperation / economics
  • Reoperation / methods
  • Retrospective Studies
  • Treatment Outcome

Substances

  • Anti-Bacterial Agents
  • Bone Cements