Are adenine strands helical H-aggregates?

J Phys Chem B. 2007 Oct 11;111(40):11812-6. doi: 10.1021/jp070403m. Epub 2007 Sep 20.

Abstract

On the basis of our quantum mechanical calculation, we propose that homogeneous single-stranded adenine bases (Ade-DNA) form helical H aggregates, and the photoexcited states can be described as Frenkel excitons. The calculated excitonic coupling between adjacent transition dipoles is in good agreement with the measured absorption spectrum of 20-base homogeneous adenine stacks that exhibits a blue shift of 2.6 nm relative to that of the monomeric species.

Publication types

  • Research Support, Non-U.S. Gov't
  • Review

MeSH terms

  • Nucleic Acid Conformation*
  • Poly A / chemistry*
  • Spectrophotometry

Substances

  • Poly A
  • poly(dA)