Pseudomonas aeruginosa choroidal abscess in a patient with bronchiectasis

Int Ophthalmol. 2008 Aug;28(4):287-90. doi: 10.1007/s10792-007-9126-x. Epub 2007 Aug 9.

Abstract

Purpose: To report a case of Pseudomonas aeruginosa endophthalmitis with choroidal abscess formation in a patient with bronchiectasis.

Methods: Case report.

Results: A 75-year-old gentleman with bronchiectasis and P. aeruginosa pneumonia developed painless loss of right eye vision. The patient had previously undergone bronchoscopy to exclude pulmonary neoplasm. Slit-lamp examination revealed intense anterior chamber inflammation with hypopyon and B-scan ophthalmic ultrasound showed a choroidal mass consistent with choroidal abscess. Systemic and topical antibiotics did not prevent further progression of the infection. Patient declined pars plana vitrectomy and opted for enucleation. Polymerase-chain-reaction-based restriction fragment-length polymorphism (PCR-RFLP) of the enucleated eye confirmed P. aeruginosa to be the causative organism.

Conclusion: P. aeruginosa cannot be completely eradicated by systemic antibiotics, and bronchial colonization of P. aeruginosa can remain a potential source for metastatic infection. P. aeruginosa choroidal abscess, previously reported only in patients with cystic fibrosis, can also occur in bronchiectasis. Physicians should therefore have a high index of suspicion of endogenous endophthalmitis and treat aggressively, especially in patients with subretinal invasion and abscess formation.

Publication types

  • Case Reports
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Abscess / diagnosis
  • Abscess / microbiology*
  • Abscess / surgery
  • Aged
  • Bronchiectasis / diagnosis
  • Bronchiectasis / microbiology*
  • Bronchiectasis / surgery
  • Choroid / microbiology
  • Choroid Diseases / diagnosis
  • Choroid Diseases / microbiology*
  • Choroid Diseases / surgery
  • DNA, Bacterial / analysis
  • Diagnosis, Differential
  • Eye Infections, Bacterial / diagnosis
  • Eye Infections, Bacterial / microbiology*
  • Eye Infections, Bacterial / surgery
  • Humans
  • Male
  • Polymerase Chain Reaction
  • Pseudomonas Infections / diagnosis
  • Pseudomonas Infections / microbiology*
  • Pseudomonas Infections / surgery
  • Pseudomonas aeruginosa / genetics
  • Pseudomonas aeruginosa / isolation & purification*
  • Vitrectomy

Substances

  • DNA, Bacterial