Sustained measles elimination in Australia and priorities for long term maintenance

Vaccine. 2007 May 4;25(18):3574-80. doi: 10.1016/j.vaccine.2007.01.090. Epub 2007 Jan 31.

Abstract

We used the 2002 national serosurvey to evaluate a primary care-based young adult vaccination campaign, measure the reproductive number (R) and, together with vaccination coverage estimates, predict R until 2012. The campaign had no impact on immunity in young adults. R was estimated to be 0.69 and predicted to stay well below the epidemic threshold of 1 until at least 2012, indicating that Australia should remain free of endemic measles in the medium term. To maintain elimination in the longer term, the timeliness and coverage of childhood vaccinations must improve and innovative strategies will be required to improve measles immunity among young adults. This experience is likely to apply to developed countries that have achieved or are approaching measles elimination.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adolescent
  • Adult
  • Antibodies, Viral / blood*
  • Australia / epidemiology
  • Child
  • Child, Preschool
  • Humans
  • Immunization Programs*
  • Immunization Schedule
  • Immunoglobulin G / blood
  • Infant
  • Measles / epidemiology*
  • Measles / immunology
  • Measles / prevention & control*
  • Measles / virology
  • Measles virus / immunology*
  • Measles-Mumps-Rubella Vaccine / administration & dosage*
  • Measles-Mumps-Rubella Vaccine / immunology
  • Seroepidemiologic Studies
  • Time Factors

Substances

  • Antibodies, Viral
  • Immunoglobulin G
  • Measles-Mumps-Rubella Vaccine