Abstract
Increased risk of severe and resistant anaphylactic shock is a rare and not widely known adverse effect of beta-blocker treatment. It is illustrated in a case of refractory anaphylactic shock occurring in a 47-year-old woman who received beta-blockers. Actually, beta-blockers increase the release of anaphylactic mediators, decrease the cardiovascular compensatory changes to the anaphylactic shock and promote paradoxical reflex vagotonic effects when using epinephrine.
MeSH terms
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Adrenergic beta-Agonists / adverse effects*
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Adrenergic beta-Agonists / therapeutic use
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Adrenergic beta-Antagonists / adverse effects*
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Amoxicillin / adverse effects*
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Anaphylaxis* / chemically induced
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Anaphylaxis* / drug therapy
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Anti-Infective Agents / adverse effects*
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Drug Administration Schedule
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Drug Antagonism
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Drug Synergism
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Emergency Medical Services / methods
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Emergency Treatment / adverse effects
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Emergency Treatment / methods
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Epinephrine / adverse effects*
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Epinephrine / therapeutic use
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Female
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Humans
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Hypertension / drug therapy
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Medical History Taking
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Medication Errors / adverse effects
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Middle Aged
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Practice Guidelines as Topic
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Risk Factors
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Self Administration / adverse effects
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Vasoconstrictor Agents / adverse effects*
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Vasoconstrictor Agents / therapeutic use
Substances
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Adrenergic beta-Agonists
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Adrenergic beta-Antagonists
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Anti-Infective Agents
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Vasoconstrictor Agents
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Amoxicillin
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Epinephrine