Tuberculosis epidemiology in six provinces of Vietnam after the introduction of the DOTS strategy

Int J Tuberc Lung Dis. 2006 Sep;10(9):963-9.

Abstract

Setting: Six provinces in Vietnam where the DOTS strategy was introduced in 1989.

Objective: To assess the impact of improved tuberculosis (TB) control on TB epidemiology in Vietnam.

Methods: Data from the surveillance system in the period 1990-2003 were analysed to assess trends of notification rates and the mean ages of notified cases. Data from repeated tuberculin surveys in the period 1986-2002 were estimated to assess the prevalence of TB infection, the annual risk of infection and its trend using various cut-off points in those with and without bacille Calmette-Guérin (BCG) scar.

Results: Age-standardised notification rates in the period 1996-2003 declined significantly, by 2.6% to 5.9% per year, in five provinces. However, in four provinces notification rates in the age group 15-24 years increased significantly, by 4.5% to 13.6% per year, during this period. The mean age of newly diagnosed patients with smear-positive TB increased up to 1995 but decreased thereafter. The annual risk of TB infection showed a significant annual decrease (4.9% per year) in one province in surveys performed between 1986 and 1997, and in two provinces (6.6% and 4.7%) in surveys conducted between 1993 and 2002.

Conclusion: These data suggest limited impact to date of the DOTS strategy in Vietnam.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adolescent
  • Adult
  • Aged
  • Child
  • Directly Observed Therapy*
  • Humans
  • Middle Aged
  • Tuberculosis, Pulmonary / drug therapy*
  • Tuberculosis, Pulmonary / epidemiology*
  • Vietnam / epidemiology