Tumour surveillance in Beckwith-Wiedemann syndrome and hemihyperplasia: a critical review of the evidence and suggested guidelines for local practice

Tiong Y Tan; David J Amor

doi:10.1111/j.1440-1754.2006.00908.x

Tumour surveillance in Beckwith-Wiedemann syndrome and hemihyperplasia: a critical review of the evidence and suggested guidelines for local practice

J Paediatr Child Health. 2006 Sep;42(9):486-90. doi: 10.1111/j.1440-1754.2006.00908.x.

Authors

Tiong Y Tan¹, David J Amor

Affiliation

¹ Genetic Health Services Victoria, Melbourne, Australia. tiong.tan@ghsv.org.au

PMID: 16925531
DOI: 10.1111/j.1440-1754.2006.00908.x

Abstract

There is strong evidence for an association between overgrowth disorders such as Beckwith-Wiedemann syndrome and the development of neoplasia. An increased cancer risk has also been observed in individuals with isolated hemihyperplasia. We critically review the evidence for tumour surveillance in Beckwith-Wiedemann syndrome and isolated hemihyperplasia and suggest local practice guidelines.

Publication types

Review

MeSH terms

Abdomen / diagnostic imaging
Beckwith-Wiedemann Syndrome / complications*
Beckwith-Wiedemann Syndrome / genetics
Hepatoblastoma / diagnosis*
Hepatoblastoma / etiology
Humans
Hyperplasia / genetics
Risk
Ultrasonography
Wilms Tumor / diagnosis*
Wilms Tumor / etiology
alpha-Fetoproteins / analysis

Substances

alpha-Fetoproteins