Abstract
Highly pathogenic H5N1 avian influenza A viruses have been spreading among domestic poultry, wild aquatic birds, and humans in many Asian countries since 2003. The largest number of patients, to date, infected with the H5N1 viruses are in Vietnam, where these viruses continue to cause outbreaks in domestic poultry. Here, we molecularly characterized the hemagglutinin and neuraminidase genes of nine H5N1 viruses isolated between January 2004 and August 2005 from domestic poultry in Vietnam. We found that several groups of highly pathogenic H5N1 avian influenza viruses are circulating among these birds, which suggests that H5N1 viruses of different lineages have been introduced into Vietnam multiple times.
Publication types
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Research Support, Non-U.S. Gov't
MeSH terms
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Amino Acid Sequence
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Animals
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Disease Outbreaks
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Genes, Viral
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Hemagglutinin Glycoproteins, Influenza Virus / classification
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Hemagglutinin Glycoproteins, Influenza Virus / genetics*
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Hemagglutinin Glycoproteins, Influenza Virus / isolation & purification
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Hemagglutinins / genetics*
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Humans
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Influenza A Virus, H5N1 Subtype / classification
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Influenza A Virus, H5N1 Subtype / genetics*
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Influenza A Virus, H5N1 Subtype / isolation & purification
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Influenza in Birds / epidemiology
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Influenza in Birds / transmission
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Influenza in Birds / virology*
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Neuraminidase / genetics*
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Phylogeny
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Poultry
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Poultry Diseases / epidemiology
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Poultry Diseases / transmission
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Poultry Diseases / virology*
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Risk Factors
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Sequence Alignment
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Vietnam / epidemiology
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Virulence
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Zoonoses
Substances
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Hemagglutinin Glycoproteins, Influenza Virus
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Hemagglutinins
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Neuraminidase