Treatment of cystic epithelial downgrowth with intralesional administration of mitomycin C

Cornea. 2005 Oct;24(7):884-6. doi: 10.1097/01.ico.0000157410.68148.d6.

Abstract

Purpose: To report a case of postoperative cystic epithelial downgrowth treated with needle aspiration and intralesional administration of mitomycin C.

Methods: Case report. A 60-year-old woman with a history of right cataract surgery 7 years ago presented with decreased vision of 1/60. The reduced vision was diagnosed secondary to a large acquired cystic epithelial downgrowth on the surface of the iris occluding the pupil.

Results: The cystic epithelial downgrowth was treated with aspiration and intralesional administration of mitomycin C solution. There was no evidence of recurrence on follow-up 1 year after the procedure.

Conclusions: Treatment of acquired cystic epithelial downgrowth with needle aspiration and intralesional administration of mitomycin C resulted in a satisfactory outcome without undertaking more extensive and invasive surgical treatments.

Publication types

  • Case Reports

MeSH terms

  • Antibiotics, Antineoplastic / administration & dosage*
  • Cataract Extraction
  • Combined Modality Therapy
  • Corneal Diseases / drug therapy*
  • Corneal Diseases / etiology
  • Cysts / drug therapy*
  • Cysts / etiology
  • Drainage / methods
  • Epithelium, Corneal / drug effects*
  • Epithelium, Corneal / pathology
  • Female
  • Humans
  • Injections, Intralesional
  • Iris Diseases / drug therapy*
  • Iris Diseases / etiology
  • Middle Aged
  • Mitomycin / administration & dosage*
  • Postoperative Complications*

Substances

  • Antibiotics, Antineoplastic
  • Mitomycin