Age-related anthropometric remodelling resulting in increased and redistributed adiposity is associated with increases in the prevalence of cardiovascular risk factors in Chinese subjects

Diabetes Metab Res Rev. 2006 Jan-Feb;22(1):72-8. doi: 10.1002/dmrr.581.

Abstract

Background: Ageing promotes increases in the prevalence of components of the metabolic syndrome, which obesity often underlies.

Methods: We report the relationship between ageing, obesity and other cardiovascular risk factors in 694 community-based Chinese subjects in gender-specific groups of three age ranges: 20.0-39.9 (young), 40.0-59.9 (middle-aged) and 60.0-79.9 (old-aged) years.

Results: Body mass index (BMI) values were similar in males in each age group, but waist and percentage body fat increased (6.6, and 39.5%, both p < 0.001, respectively), from young to old-age groups, as did blood pressure and glycated haemoglobin levels (all p < 0.001). In the females, increases (all p < 0.001) in percentage body fat (29.3%) were accompanied by greater increases in BMI (10.3%) and waist (19.2%) than the males. Blood pressure, glycated haemoglobin, total and LDL-cholesterol and triglyceride levels increased linearly with age (all p < 0.001).

Conclusion: Age-related increases in central adiposity and percentage body fat were associated with increasingly adverse cardiovascular risk factor profiles.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adipose Tissue
  • Adiposity*
  • Adult
  • Aged
  • Aged, 80 and over
  • Aging*
  • Blood Pressure
  • Body Composition
  • Body Constitution
  • Body Mass Index
  • Cardiovascular Diseases / etiology*
  • China
  • Cholesterol, LDL / blood
  • Female
  • Glycated Hemoglobin / analysis
  • Humans
  • Male
  • Middle Aged
  • Obesity / complications*
  • Prevalence
  • Risk Factors
  • Triglycerides / blood

Substances

  • Cholesterol, LDL
  • Glycated Hemoglobin A
  • Triglycerides