Chronic oxidative stress as a central mechanism for glucose toxicity in pancreatic islet beta cells in diabetes

J Biol Chem. 2004 Oct 8;279(41):42351-4. doi: 10.1074/jbc.R400019200. Epub 2004 Jul 16.
No abstract available

Publication types

  • Review

MeSH terms

  • Animals
  • Antioxidants
  • Blood Glucose / metabolism*
  • Diabetes Mellitus / pathology*
  • Gene Expression Regulation
  • Glucose / toxicity*
  • Humans
  • Hyperglycemia
  • Insulin / metabolism
  • Islets of Langerhans / metabolism*
  • Models, Biological
  • Oxidative Stress
  • Reactive Oxygen Species

Substances

  • Antioxidants
  • Blood Glucose
  • Insulin
  • Reactive Oxygen Species
  • Glucose