Screening of colonic tumors by air-inflated magnetic resonance (MR) colonography

J Magn Reson Imaging. 2004 Apr;19(4):447-52. doi: 10.1002/jmri.20028.

Abstract

Purpose: To assess the accuracy of air-inflated magnetic resonance (MR) colonography for the detection of colonic lesions.

Materials and methods: A total of 36 patients underwent both colonoscopy and air-inflated MR colonography. Breath-hold sequences (volumetric interpolated breath-hold examination (VIBE) coronal, and half-Fourier acquisition single-shot turbo spin-echo (HASTE) axial and coronal, both supine and prone) were performed with a 1.5T scanner. The detection of colonic lesions by MR colonography was then correlated with the findings from the colonoscopy performed on the same day.

Results: Two patients were unable to complete the MR colonography examination. Analysis was based on the results from 34 patients (17 males and 17 females, 38-70 years old, mean age = 54.9 years) who completed both examinations. MR colonography depicted two of two colonic tumors, one of one P4 (> 2 cm) polyp, one of two P2 (0.5-1 cm) polyps, and two of 11 P1 (< 0.5 cm) polyps. False-positive MR colonography interpretations were noted for one P1 polyp and two P2 polyps. The overall sensitivity, positive predictive value, and accuracy of MR colonography were 38%, 67%, and 46.2%, respectively. For the detection of endoluminal lesions > 5 mm, air-inflated MR colonography yielded a sensitivity of 75%, specificity of 93.3%, accuracy of 91.2%, positive predictive value of 60%, and negative predictive value of 96.6%.

Conclusion: Air-inflated MR colonography is a new technique that deserves further investigation.

MeSH terms

  • Adult
  • Aged
  • Air
  • Colon / pathology*
  • Colonic Neoplasms / diagnosis*
  • Colonic Polyps / diagnosis
  • Colonoscopy
  • False Positive Reactions
  • Female
  • Humans
  • Image Processing, Computer-Assisted
  • Insufflation
  • Magnetic Resonance Imaging / adverse effects
  • Magnetic Resonance Imaging / methods*
  • Male
  • Middle Aged
  • Patient Satisfaction
  • Predictive Value of Tests
  • Sensitivity and Specificity