Abstract
We report a case of chronic myelomonocytic leukemia (CMMoL) with unusual features and an isochromosome 14q as the sole abnormality. A review of the literature suggests that isochromosome 14q (or trisomy 14) is a marker of leukemia with dysplastic features.
MeSH terms
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Anemia, Refractory, with Excess of Blasts / complications
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Cell Transformation, Neoplastic
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Chromosomes, Human, Pair 14*
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Gene Expression Regulation, Leukemic
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Humans
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Hypergammaglobulinemia / complications
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Leukemia, Myelomonocytic, Chronic / etiology
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Leukemia, Myelomonocytic, Chronic / genetics*
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Male
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Middle Aged
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Red-Cell Aplasia, Pure / complications
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Trisomy*