Cholangitis after hepatic portoenterostomy for biliary atresia: a multivariate analysis of risk factors

J Pediatr. 2003 May;142(5):566-71. doi: 10.1067/mpd.2003.195.

Abstract

Cholangitis occurred in 59% of 77 patients who underwent the portoenterostomy procedure for biliary atresia between 1980 and 2000. Good postoperative bile drainage was associated with a lower risk of cholangitis than partial (odds ratio, 5.72; 95% CI, 2.89-11.3) or poor (odds ratio, 3.29; 95% CI, 1.89-5.7) bile drainage. Cholangitis was not an independent risk factor for death or liver transplantation.

MeSH terms

  • Biliary Atresia / surgery*
  • Cephalosporins / therapeutic use
  • Cholangitis / drug therapy
  • Cholangitis / etiology*
  • Female
  • Follow-Up Studies
  • Humans
  • Infant
  • Male
  • Multivariate Analysis
  • Portoenterostomy, Hepatic / adverse effects*
  • Portoenterostomy, Hepatic / methods
  • Retrospective Studies
  • Risk Factors
  • Survival Rate

Substances

  • Cephalosporins