GENECOUNTING: haplotype analysis with missing genotypes

Jing Hua Zhao; Sebastien Lissarrague; Laurent Essioux; Pak Chung Sham

doi:10.1093/bioinformatics/18.12.1694

GENECOUNTING: haplotype analysis with missing genotypes

Bioinformatics. 2002 Dec;18(12):1694-5. doi: 10.1093/bioinformatics/18.12.1694.

Authors

Jing Hua Zhao¹, Sebastien Lissarrague, Laurent Essioux, Pak Chung Sham

Affiliation

¹ Department of Epidemiology and Public Health, University College London, 1-19 Torrington Place, London WC1E 6BT, UK. j.zhao@public-health.ucl.ac.uk

PMID: 12490459
DOI: 10.1093/bioinformatics/18.12.1694

Abstract

A general algorithm is described for haplotype analysis of unrelated individuals with missing genotypes. It can handle problems involving multiple polymorphic markers with missing data.

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Algorithms*
Alleles
Gene Frequency*
Genetic Markers / genetics
Genotype*
Haplotypes / genetics*
Likelihood Functions
Sequence Analysis, DNA / methods*
Software

Substances

Genetic Markers