The Kirschner operation in unresectable esophageal cancer: current application

Arch Surg. 2002 Nov;137(11):1228-32. doi: 10.1001/archsurg.137.11.1228.

Abstract

Hypothesis: With the introduction of safe, effective nonoperative alternatives, bypass surgery for unresectable esophageal cancer is infrequently performed, but it has a limited role in palliation of esophageal cancer that needs to be defined.

Design: Retrospective cohort study.

Setting: Department of Surgery at Queen Mary Hospital in Hong Kong.

Patients: Patients who had unresectable esophageal cancer and underwent bypass surgery between January 1, 1991, and December 31, 1998.

Intervention: Bypass procedures were performed using a gastric or colonic conduit to the neck.

Main outcome measures: Morbidity and mortality and quality of palliation.

Results: Thirty-eight patients underwent retrosternal bypass to the neck using a gastric (n = 27) or colonic (n = 11) conduit. Ten patients (26%) underwent unplanned bypass at the time of exploration for resection because of unexpected findings of T4 disease (n = 2) or technical difficulties in addition to advanced disease (n = 8). Between 1991 and 1994, 1 of 26 bypasses was unplanned and the hospital mortality was 42% (11/26), while between 1995 and 1998, 9 of 12 bypasses were unplanned and the hospital mortality was 8% (1/12). There were 12 hospital deaths in the planned bypass group (n = 28) and none in the unplanned bypass (n = 10) group (43% vs 0%, P =.01). The median survival in patients who underwent unplanned bypass was 6.9 months, compared with 1.9 months in patients who underwent planned bypass (P =.004). All patients were discharged from the hospital on at least a semisolid diet.

Conclusions: The Kirschner operation is largely obsolete as a planned procedure because of high morbidity and mortality. Bypass surgery, however, is a reasonable option as an unplanned procedure when resection is precluded at the time of exploration because of unexpected adverse operative findings.

MeSH terms

  • Adenocarcinoma / surgery*
  • Aged
  • Carcinoma, Squamous Cell / surgery*
  • Cohort Studies
  • Colon / transplantation
  • Digestive System Surgical Procedures / methods*
  • Esophageal Neoplasms / surgery*
  • Esophagus / surgery
  • Female
  • Humans
  • Male
  • Middle Aged
  • Organ Transplantation
  • Palliative Care / methods*
  • Retrospective Studies
  • Stomach / transplantation
  • Transplantation, Autologous