Precursor T-lymphoblastic leukemia with a novel t(1;22)(p34;q13)

Cancer Genet Cytogenet. 2002 Jul 15;136(2):146-8. doi: 10.1016/s0165-4608(02)00531-9.

Abstract

A 37-year-old woman that presented with cervical lymphadenopathy and leukocytosis was found to have precursor T-lymphoblastic leukemia (T-ALL). Cytogenetic study of the leukemic cells showed a 46,XX, t(1;22)(p34;q13) karyotype. The t(1;22)(p34;q13) is a novel chromosomal abnormality in human malignancies and is probably a variant form of the t(1;14)(p34;q11) found in precursor T-ALL.

Publication types

  • Case Reports

MeSH terms

  • Adult
  • Chromosomes, Human, Pair 1*
  • Chromosomes, Human, Pair 22
  • Female
  • Humans
  • Karyotyping
  • Leukemia, Lymphoid / genetics*
  • Translocation, Genetic*